TB-500 is a synthetic version of the naturally occurring peptide Thymosin Beta-4, which plays a key role in tissue regeneration. It functions by promoting actin polymerization, a fundamental process for cell migration and healing, thereby accelerating repair of muscle, tendon, and other tissues. Its relevance to healthspan lies in its potential to mitigate age-related decline in repair capacity and reduce chronic inflammation.
Verdict
Experimental for tissue repair, but unproven and risky for general healthspan.
HEALTHSPAN IMPACT
Experimental
RISK LEVEL
High
EVIDENCE GRADE
C
MONTHLY COST
$50 - $300
Protocol
- A loading phase of 2-6 mg weekly, divided into 2-3 injections, for 4-6 weeks.
- A maintenance phase of 2-5 mg administered once or twice per month.
Flags
- Not approved for human use by the FDA or any major regulatory body.
- Sourced from unregulated 'research chemical' suppliers, risking purity and safety issues.
- Long-term safety profile in healthy humans is unknown.
- Theoretical risk of promoting growth of pre-existing cancers due to angiogenic properties.
- Banned by the World Anti-Doping Agency (WADA) as a performance-enhancing substance.