Meta Information

ID:tb-500

Name:TB-500

Schema Version:1.5

Title

TB-500

Alternate Names

• Thymosin Beta-4

Intervention Type

therapeutic_agent

Expected Cost Mean

Low Cost:

50

High Cost:

300

Cost Type:

monthly

Description:

Cost for research-grade peptide vials from online suppliers, varies by phase.

Summary

TB-500 is a synthetic version of the naturally occurring peptide Thymosin Beta-4, which plays a key role in tissue regeneration. It functions by promoting actin polymerization, a fundamental process for cell migration and healing, thereby accelerating repair of muscle, tendon, and other tissues. Its relevance to healthspan lies in its potential to mitigate age-related decline in repair capacity and reduce chronic inflammation.

Purpose

A synthetic peptide promoting tissue repair and reducing inflammation.

Card Summary

A synthetic peptide mimicking natural Thymosin Beta-4, used to accelerate tissue repair, reduce systemic inflammation, and support cellular regeneration.

Drug Class

Drugs In Class

Empty Array

Impact

Score:

3.5

Justification:

Primarily supports tissue repair; lacks robust human data for systemic longevity benefits.

Evidence

Grade:

C

Score:

3

Justification:

Evidence is limited to animal models and in-vitro studies; lacks human RCTs.

Safety

Score:

7.5

Justification:

Unregulated research chemical with unknown long-term safety profile and potential pro-angiogenic risks.

Flags

• Not approved for human use by the FDA or any major regulatory body.
• Sourced from unregulated 'research chemical' suppliers, risking purity and safety issues.
• Long-term safety profile in healthy humans is unknown.
• Theoretical risk of promoting growth of pre-existing cancers due to angiogenic properties.
• Banned by the World Anti-Doping Agency (WADA) as a performance-enhancing substance.

Verdict

Experimental for tissue repair, but unproven and risky for general healthspan.

Created

2026-04-24T00:13:18.005034Z

Model

Gemini 3.1 Pro (High)

Delivery

Route:

subcutaneous_injection

Scope:

• systemic

Indication

Focus:

healthspan

Description:

TB-500 is a synthetic version of the naturally occurring peptide Thymosin Beta-4, which plays a key role in tissue regeneration. It functions by promoting actin polymerization, a fundamental process f...

Typical Protocol

• A loading phase of 2-6 mg weekly, divided into 2-3 injections, for 4-6 weeks.
• A maintenance phase of 2-5 mg administered once or twice per month.