Passionflower is an herbal supplement primarily used for its anxiolytic (anxiety-reducing) and mild sedative properties. Its mechanism is thought to involve the modulation of the GABA neurotransmitter system, which promotes relaxation. From a healthspan perspective, its value is indirect, stemming from its potential to improve sleep quality and mitigate the physiological damage of chronic stress, both of which are linked to accelerated aging.
Verdict
A reasonable, low-risk option for mild anxiety and sleep support.
HEALTHSPAN IMPACT
Moderate
RISK LEVEL
Low
EVIDENCE GRADE
B
MONTHLY COST
$10 - $25
Protocol
- For anxiety, take 200-500 mg of standardized extract one to two times daily.
- For sleep, drink one cup of tea or take 400-800 mg of extract 30-60 minutes before bed.
Flags
- May cause drowsiness; avoid operating heavy machinery until effects are known.
- Potentiates effects of other sedatives, including alcohol, benzodiazepines, and barbiturates.
- Avoid during pregnancy and breastfeeding due to insufficient safety data.