Magnesium is an essential mineral and a critical cofactor in over 300 enzymatic systems vital for healthspan. It plays a fundamental role in ATP production, DNA repair, muscle function, and nervous system regulation. Given that dietary insufficiency is common, supplementation can restore optimal function in these core biological processes, potentially mitigating age-related decline in metabolic and neurological health.
Verdict
A safe, foundational supplement to correct common dietary shortfalls.
HEALTHSPAN IMPACT
High Value
RISK LEVEL
Low
EVIDENCE GRADE
A
MONTHLY COST
$5 - $15
Protocol
- Take 200-400 mg of elemental magnesium daily, often in the evening to support sleep.
Flags
- High doses can cause a significant laxative effect.
- Can interfere with the absorption of certain antibiotics (tetracyclines, quinolones) and bisphosphonates.
- Individuals with kidney disease should consult a physician before supplementing.