Meta Information

ID:magnesium-citrate

Name:Magnesium Citrate

Schema Version:1.5

Alternate Names

• Magnesium

Intervention Type

therapeutic_agent

Expected Cost Mean

Low Cost:

5

High Cost:

15

Cost Type:

monthly

Description:

Widely available and inexpensive over-the-counter supplement.

Summary

Magnesium is an essential mineral and a critical cofactor in over 300 enzymatic systems vital for healthspan. It plays a fundamental role in ATP production, DNA repair, muscle function, and nervous system regulation. Given that dietary insufficiency is common, supplementation can restore optimal function in these core biological processes, potentially mitigating age-related decline in metabolic and neurological health.

Purpose

Essential mineral for energy production, DNA repair, and sleep.

Card Summary

An essential mineral and enzymatic cofactor crucial for mitochondrial energy production, DNA stability, and nervous system regulation, often supplemented to correct common dietary insufficiencies.

Drug Class

magnesium

Drugs In Class

Empty Array

Impact

Score:

7.5

Justification:

Corrects common deficiencies impacting hundreds of critical enzymatic processes.

Evidence

Grade:

A

Score:

9

Justification:

Extensive human RCTs and meta-analyses confirm its role in numerous health outcomes.

Safety

Score:

3

Justification:

Generally recognized as safe (GRAS); primary side effect is dose-dependent laxative effect.

Flags

• High doses can cause a significant laxative effect.
• Can interfere with the absorption of certain antibiotics (tetracyclines, quinolones) and bisphosphonates.
• Individuals with kidney disease should consult a physician before supplementing.

Verdict

A safe, foundational supplement to correct common dietary shortfalls.

Created

2026-04-25T22:21:31.850569Z

Model

Gemini 3.1 Pro (High)

Delivery

Route:

oral

Scope:

• systemic

Indication

Focus:

healthspan

Description:

Magnesium is an essential mineral and a critical cofactor in over 300 enzymatic systems vital for healthspan. It plays a fundamental role in ATP production, DNA repair, muscle function, and nervous sy...

Typical Protocol

• Take 200-400 mg of elemental magnesium daily, often in the evening to support sleep.