Meta Information
ID:green-lipped-mussel
Name:
Schema Version:AIM-2.0
Interactions
Target id:
/condition/shellfish-allergy
Target name:
Shellfish Allergy
Severity:
major
Interaction type:
adverse
Nature:
absolute
Temporal spacing:
null
Description:
Green-lipped mussel is a type of shellfish; individuals with a shellfish allergy can experience severe allergic reactions, including anaphylaxis.
Actionable advice:
Avoid completely if you have a known or suspected shellfish allergy.
Target id:
/class/anticoagulants-antiplatelets
Target name:
Anticoagulants and Antiplatelets
Severity:
moderate
Interaction type:
adverse
Nature:
absolute
Temporal spacing:
null
Description:
Green-lipped mussel extract contains omega-3 fatty acids and has mild anti-inflammatory effects that can inhibit platelet aggregation, potentially increasing the risk of bleeding when combined with blood-thinning medications.
Actionable advice:
Consult your doctor before combining; increased monitoring for bruising or bleeding may be necessary.
Target id:
/procedure/surgery
Target name:
Surgery
Severity:
major
Interaction type:
adverse
Nature:
temporal
Temporal spacing:
Hours before target:
336
Hours after target:
null
Description:
Due to its potential to inhibit platelet aggregation and thin the blood, green-lipped mussel extract may increase the risk of excessive bleeding during and after surgical procedures.
Actionable advice:
Discontinue use at least 2 weeks prior to any scheduled surgery and inform your surgeon.
Target id:
/condition/pregnancy
Target name:
Pregnancy
Severity:
major
Interaction type:
adverse
Nature:
absolute
Temporal spacing:
null
Description:
The safety of green-lipped mussel extract during pregnancy has not been established, and it should be avoided due to unknown risks to the fetus.
Actionable advice:
Do not use during pregnancy due to a lack of safety data.
Target id:
/condition/lactation
Target name:
Breastfeeding (Lactation)
Severity:
major
Interaction type:
adverse
Nature:
absolute
Temporal spacing:
null
Description:
It is unknown if components of green-lipped mussel extract pass into breast milk or what effects they may have on a nursing infant.
Actionable advice:
Avoid use while breastfeeding due to insufficient safety information.
Target id:
/condition/bleeding-disorders
Target name:
Bleeding Disorders
Severity:
major
Interaction type:
adverse
Nature:
absolute
Temporal spacing:
null
Description:
The antiplatelet effects of green-lipped mussel extract can exacerbate bleeding tendencies in individuals with pre-existing bleeding disorders like hemophilia or von Willebrand disease.
Actionable advice:
Avoid use if you have a bleeding disorder unless approved and monitored by a hematologist.
Target id:
/dietary/meal
Target name:
Any Caloric Meal
Severity:
moderate
Interaction type:
requirement
Nature:
temporal
Temporal spacing:
Hours before target:
0
Hours after target:
0
Description:
Taking green-lipped mussel extract with food, particularly a meal containing some fat, can enhance the absorption of its lipid components and reduce the risk of gastrointestinal side effects like nausea.
Actionable advice:
Always take with a meal to improve absorption and minimize stomach upset.
Target id:
/class/antihypertensives
Target name:
Antihypertensive Medications
Severity:
minor
Interaction type:
adverse
Nature:
absolute
Temporal spacing:
null
Description:
The omega-3 fatty acids in green-lipped mussel extract may have a mild blood pressure-lowering effect, which could be additive with antihypertensive medications, potentially increasing the risk of hypotension (low blood pressure).
Actionable advice:
Monitor blood pressure if combining with blood pressure medications, especially when starting.
Target id:
/class/herbal-anticoagulants
Target name:
Herbal Anticoagulants/Antiplatelets
Severity:
minor
Interaction type:
adverse
Nature:
absolute
Temporal spacing:
null
Description:
Combining green-lipped mussel with other supplements that have blood-thinning properties (e.g., fish oil, ginkgo, garlic) can have an additive effect, theoretically increasing the risk of bleeding or bruising.
Actionable advice:
Use caution when combining with other supplements known to affect blood clotting.
Target id:
/class/antidiabetic-medications
Target name:
Diabetes Medications
Severity:
minor
Interaction type:
adverse
Nature:
absolute
Temporal spacing:
null
Description:
Omega-3 fatty acids may slightly affect blood glucose levels. This could potentially enhance the effects of diabetes medications, increasing the risk of hypoglycemia (low blood sugar).
Actionable advice:
Monitor blood sugar levels closely when starting this supplement if you are on diabetes medication.
Target id:
/class/nsaids
Target name:
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Severity:
minor
Interaction type:
synergistic
Nature:
absolute
Temporal spacing:
null
Description:
Both green-lipped mussel extract and NSAIDs inhibit inflammatory pathways. This combination may provide an additive anti-inflammatory effect, but could also theoretically increase the risk of gastrointestinal side effects.
Actionable advice:
May be taken together for an additive effect, but discuss with your doctor, especially if you have a history of GI issues.
Target id:
/condition/asthma-copd
Target name:
Asthma and COPD
Severity:
minor
Interaction type:
adverse
Nature:
absolute
Temporal spacing:
null
Description:
While studied for its anti-leukotriene benefits in asthma, some individuals, particularly those with shellfish sensitivity, may experience a paradoxical worsening of respiratory symptoms.
Actionable advice:
Use with caution if you have asthma and monitor for any changes in breathing, especially when first starting.