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Cissus Quadrangularis

Veldt Grape, Devil's Backbone, Hadjod

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Supports bone density, joint health, and metabolic function.

Cissus Quadrangularis is a medicinal plant traditionally used for bone and joint health. Its active compounds, such as ketosterones, may support bone healing and reduce joint pain, indirectly promoting healthspan by maintaining mobility and physical function. Some limited evidence also suggests potential benefits for metabolic health.

Verdict

Consider for specific joint or bone issues; not a core longevity supplement.

HEALTHSPAN IMPACT

Experimental

RISK LEVEL

Low

EVIDENCE GRADE

B

MONTHLY COST

$15 - $30

Protocol

  • A typical dose is 500-1000 mg daily, often split into two administrations.

Flags

  • May lower blood sugar; use with caution if taking diabetes medications.
  • Safety during pregnancy and breastfeeding has not been established.