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Centella Asiatica (Cica)

Cica, Gotu Kola, Brahmi, Asiatic Pennywort

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Supports cognitive function, vascular health, and skin integrity.

Centella asiatica contains active compounds called triterpenoids that support collagen synthesis, reduce inflammation, and may improve cerebral blood flow. Its healthspan relevance lies in promoting cognitive function, enhancing vascular integrity, and protecting skin health, all of which can decline with age.

Verdict

A reasonable supplement for targeted cognitive and vascular support.

HEALTHSPAN IMPACT

Moderate

RISK LEVEL

Low

EVIDENCE GRADE

B

MONTHLY COST

$10 - $30

Protocol

  • Take 250-750 mg of a standardized extract daily, often split into two doses.

Flags

  • Monitor liver function with long-term, high-dose use.
  • May have a mild sedative effect; use caution with other sedatives.
  • Potential interaction with drugs metabolized by the liver (CYP enzymes).