Meta Information
ID:centella-asiatica
Name:Centella Asiatica (Cica)
Schema Version:1.5
Alternate Names
- Cica
- Gotu Kola
- Brahmi
- Asiatic Pennywort
Intervention Type
therapeutic_agent
Expected Cost Mean
Low Cost:
10
High Cost:
30
Cost Type:
monthly
Description:
Widely available as an affordable, non-prescription herbal supplement.
Summary
Centella asiatica contains active compounds called triterpenoids that support collagen synthesis, reduce inflammation, and may improve cerebral blood flow. Its healthspan relevance lies in promoting cognitive function, enhancing vascular integrity, and protecting skin health, all of which can decline with age.
Purpose
Supports cognitive function, vascular health, and skin integrity.
Card Summary
A plant extract supporting brain, vascular, and skin health.
Drug Class
Drugs In Class
Empty Array
Impact
Score:
4.5
Justification:
Targeted benefits for cognitive function and vascular health, but not a systemic driver.
Evidence
Grade:
B
Score:
5.5
Justification:
Some human RCTs exist for cognition and venous insufficiency, but larger trials are needed.
Safety
Score:
3
Justification:
Generally well-tolerated with a long history of use; rare reports of liver issues.
Flags
- Monitor liver function with long-term, high-dose use.
- May have a mild sedative effect; use caution with other sedatives.
- Potential interaction with drugs metabolized by the liver (CYP enzymes).
Verdict
A reasonable supplement for targeted cognitive and vascular support.
Created
2026-04-26T18:50:23.096704Z
Model
Gemini 3.1 Pro (High)
Delivery
Route:
oral
Scope:
- systemic
Indication
Focus:
healthspan
Description:
Centella asiatica contains active compounds called triterpenoids that support collagen synthesis, reduce inflammation, and may improve cerebral blood flow. Its healthspan relevance lies in promoting c...
Typical Protocol
- Take 250-750 mg of a standardized extract daily, often split into two doses.