Aged Garlic Extract (AGE) is produced by aging raw garlic, which converts unstable sulfur compounds into stable, water-soluble ones like S-allyl-cysteine. These compounds exert antioxidant, anti-inflammatory, and immunomodulatory effects. Its relevance to healthspan lies primarily in its well-documented ability to support cardiovascular health, improve endothelial function, modulate blood pressure, and potentially influence cellular aging pathways by reducing oxidative stress.
Verdict
Solid cardiovascular support; consider for inflammation and blood pressure.
HEALTHSPAN IMPACT
High Value
RISK LEVEL
Low
EVIDENCE GRADE
A
MONTHLY COST
$15 - $30
Protocol
- Commonly 600-1200 mg daily, often split into two doses, taken with meals.
Flags
- May interact with anticoagulant medications, increasing bleeding risk.
- Rarely causes mild gastrointestinal upset.