Meta Information
ID:aged-garlic-extract
Name:Aged Garlic Extract
Schema Version:1.5
Alternate Names
- AGE
- Kyolic Garlic Extract
Intervention Type
therapeutic_agent
Expected Cost Mean
Low Cost:
15
High Cost:
30
Cost Type:
monthly
Description:
Supplement cost, generally not covered by insurance.
Summary
Aged Garlic Extract (AGE) is produced by aging raw garlic, which converts unstable sulfur compounds into stable, water-soluble ones like S-allyl-cysteine. These compounds exert antioxidant, anti-inflammatory, and immunomodulatory effects. Its relevance to healthspan lies primarily in its well-documented ability to support cardiovascular health, improve endothelial function, modulate blood pressure, and potentially influence cellular aging pathways by reducing oxidative stress.
Purpose
Supports cardiovascular health, reduces inflammation, and modulates aging pathways.
Card Summary
Aged Garlic Extract provides stable sulfur compounds with antioxidant and anti-inflammatory properties, primarily supporting cardiovascular health and blood pressure regulation, contributing to a longer healthspan.
Drug Class
Drugs In Class
Empty Array
Impact
Score:
6.8
Justification:
Robust cardiovascular, anti-inflammatory, and antioxidant benefits.
Evidence
Grade:
A
Score:
8.5
Justification:
Multiple human RCTs and meta-analyses support cardiovascular benefits.
Safety
Score:
3
Justification:
GRAS substance with robust safety profile; minor side effects rare.
Flags
- May interact with anticoagulant medications, increasing bleeding risk.
- Rarely causes mild gastrointestinal upset.
Verdict
Solid cardiovascular support; consider for inflammation and blood pressure.
Model
Gemini 3 Flash
Delivery
Route:
oral
Scope:
- systemic
Indication
Focus:
healthspan
Description:
Aged Garlic Extract (AGE) is produced by aging raw garlic, which converts unstable sulfur compounds into stable, water-soluble ones like S-allyl-cysteine. These compounds exert antioxidant, anti-infla...
Typical Protocol
- Commonly 600-1200 mg daily, often split into two doses, taken with meals.