Vitamin C is a vital water-soluble antioxidant that protects cells from oxidative stress, a key driver of aging. It is essential for collagen synthesis, maintaining skin and connective tissue integrity, and supports robust immune function. While crucial for preventing deficiency-related diseases, its role in extending maximal healthspan in well-nourished individuals is less established.
Verdict
Essential for baseline health; supplementation offers modest benefits if diet is insufficient.
HEALTHSPAN IMPACT
Moderate
RISK LEVEL
Low
EVIDENCE GRADE
A
MONTHLY COST
$5 - $20
Protocol
- Daily oral doses for healthspan range from 200 mg to 2,000 mg.
- Higher doses are often split throughout the day to improve absorption and maintain plasma levels.
Flags
- High doses (>2,000 mg/day) may cause diarrhea, nausea, and stomach cramps.
- May increase the risk of kidney stones in susceptible individuals.
- Can interfere with certain lab tests, including blood and urine glucose tests.
- May interact with chemotherapy, radiation therapy, statins, and blood thinners like warfarin.