Meta Information
ID:urolithin-a
Name:Urolithin A
Schema Version:1.5
Title
Urolithin A
Alternate Names
- UA
Intervention Type
therapeutic_agent
Expected Cost Mean
Low Cost:
60
High Cost:
130
Cost Type:
monthly
Description:
Cost for a 30-day supply of a 500mg-1000mg daily dose.
Summary
Urolithin A is a postbiotic compound produced by gut bacteria from dietary precursors like ellagitannins, found in pomegranates and berries. Its primary healthspan relevance stems from its ability to induce mitophagy, the process of clearing out old, dysfunctional mitochondria. By improving mitochondrial quality control, Urolithin A may enhance cellular energy production and muscle function, which typically decline with age.
Purpose
A postbiotic that enhances mitochondrial health by stimulating mitophagy.
Card Summary
A gut-derived postbiotic that promotes mitophagy, clearing damaged mitochondria to improve cellular energy and muscle function.
Drug Class
Drugs In Class
Empty Array
Impact
Score:
5.5
Justification:
Targets mitochondrial health and muscle function, a key but specific aging pathway.
Evidence
Grade:
B
Score:
6.5
Justification:
Positive human RCTs exist, primarily focused on muscle function and biomarkers.
Safety
Score:
3
Justification:
Generally Recognized As Safe (GRAS) status with a good safety profile in human trials.
Flags
- Individual gut microbiomes vary in their ability to produce Urolithin A from dietary precursors.
- Much of the human research is funded by the primary commercial producer.
- Long-term safety and efficacy data in humans is still limited.
Verdict
Promising for mitochondrial health and muscle function, pending more independent research.
Created
2026-04-24T00:16:00.110202Z
Model
Gemini 3.1 Pro (High)
Delivery
Route:
oral
Scope:
- systemic
Indication
Focus:
healthspan
Description:
Urolithin A is a postbiotic compound produced by gut bacteria from dietary precursors like ellagitannins, found in pomegranates and berries. Its primary healthspan relevance stems from its ability to ...
Typical Protocol
- Daily dosages typically range from 250mg to 1000mg, often taken with food.