Meta Information
ID:uridine-monophosphate
Name:Uridine Monophosphate
Schema Version:1.5
Alternate Names
- UMP
- Uridine
Intervention Type
therapeutic_agent
Expected Cost Mean
Low Cost:
15
High Cost:
40
Cost Type:
monthly
Description:
Cost for a 30-day supply of capsules or powder, not covered by insurance.
Summary
Uridine is a pyrimidine nucleoside, a fundamental building block for RNA, crucial for synaptic formation and neuronal membrane health. By supporting the synthesis of phosphatidylcholine, a key component of cell membranes, it is thought to enhance cognitive function, synaptic plasticity, and mitochondrial biogenesis. Its healthspan relevance is primarily focused on preserving brain health and function with age.
Purpose
Supports cognitive function, neuronal repair, and mitochondrial health.
Drug Class
Drugs In Class
Empty Array
Impact
Score:
4.5
Justification:
Targeted benefits for cognitive function and neuronal health, not systemic longevity.
Evidence
Grade:
B
Score:
5.5
Justification:
Small human trials for cognition exist, but lacks large RCTs for longevity.
Safety
Score:
3
Justification:
Generally Recognized As Safe (GRAS) with a good safety profile at typical doses.
Flags
- High doses may increase uric acid levels, a concern for individuals with gout.
- Can cause mild gastrointestinal distress in sensitive individuals.
- Long-term effects of high-dose supplementation in healthy populations are not well-studied.
Verdict
A promising nootropic for brain health with limited direct longevity evidence.
Created
2026-04-27T00:56:55.324202Z
Model
Gemini 3.1 Pro (High)
Delivery
Route:
oral
Scope:
- systemic
Indication
Focus:
healthspan
Description:
Uridine is a pyrimidine nucleoside, a fundamental building block for RNA, crucial for synaptic formation and neuronal membrane health. By supporting the synthesis of phosphatidylcholine, a key compone...
Typical Protocol
- Typical doses range from 250-1000 mg daily, often taken sublingually for enhanced absorption.