Meta Information
ID:ubiquinol
Name:Ubiquinol
Schema Version:1.5
Alternate Names
- Reduced Coenzyme Q10
- Reduced CoQ10
Active Compound
ubiquinol
Intervention Type
therapeutic_agent
Delivery
Route:
oral
Scope:
- systemic
Regulatory Status
- us:dietary_supplement
- eu:food_supplement
Indication
Focus:
healthspan
Description:
Supports mitochondrial function and acts as a potent antioxidant, potentially mitigating age-related cellular decline and energy deficits.
Typical Protocol
- Typical daily doses range from 100 mg to 300 mg, often taken with a meal containing fat to improve absorption.
Expected Cost Mean
Low Cost:
25
High Cost:
60
Cost Type:
monthly
Description:
Cost for a 30-day supply of 100-200 mg daily; not covered by insurance.
Summary
Ubiquinol is the active, reduced form of Coenzyme Q10 (CoQ10), a critical component of the mitochondrial electron transport chain for ATP (energy) production. As a potent lipid-soluble antioxidant, it protects cell membranes from oxidative damage. Levels of CoQ10 naturally decline with age, and supplementation aims to restore youthful levels, supporting energy production and cellular resilience.
Purpose
Potent antioxidant supporting mitochondrial energy production and cellular health.
Card Summary
The active form of CoQ10, Ubiquinol is a potent mitochondrial antioxidant that supports cellular energy production, which declines with age.
Drug Class
Drugs In Class
Empty Array
Impact
Score:
4.5
Justification:
Supports a core aging pathway (mitochondrial function) but lacks robust healthspan extension data.
Evidence
Grade:
B
Score:
6.5
Justification:
Strong mechanistic data and human trials for specific diseases, but limited healthspan RCTs.
Safety
Score:
2.5
Justification:
Excellent safety profile with rare, mild side effects like gastrointestinal upset at high doses.
Flags
- May interact with blood thinners like warfarin, potentially reducing their effectiveness.
- Statin medications can deplete the body's natural CoQ10 levels, making supplementation potentially beneficial.
Verdict
A safe, targeted intervention for supporting mitochondrial energy and antioxidant defense.
Qualifier
route: oral, scope: systemic
Created
2026-05-14T03:00:07.700746Z
Ai Model
Gemini 2.5 Pro (High)