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SS-31

Elamipretide, Bendavia, MTP-131

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Meta Information

ID:ss-31
Name:SS-31
Schema Version:1.5

Title

SS-31

Alternate Names

  • Elamipretide
  • Bendavia
  • MTP-131

Intervention Type

therapeutic_agent

Expected Cost Mean

Low Cost:
400
High Cost:
1200
Cost Type:
monthly
Description:
Cost for research-grade chemical; not a commercially available pharmaceutical.

Summary

SS-31 is a small peptide that selectively targets the inner mitochondrial membrane, binding to cardiolipin to stabilize mitochondrial structure and function. This enhances ATP production and reduces oxidative stress, directly addressing the age-related decline in mitochondrial health, a core driver of aging. Its potential lies in restoring cellular energy and function in tissues with high energy demands, like the heart, brain, and muscles.

Purpose

A mitochondrial-targeting peptide that restores cellular energy production.

Card Summary

A research peptide that targets and revitalizes mitochondria to combat age-related energy decline.

Drug Class

mitochondrial-targeting-peptide

Drugs In Class

Empty Array

Impact

Score:
3.8
Justification:
Targets a core aging hallmark, but lacks broad human healthspan trial data.

Evidence

Grade:
C
Score:
3.5
Justification:
Promising animal data and disease-specific human trials, but no general longevity studies.

Safety

Score:
7.5
Justification:
Investigational drug with unknown long-term effects and risks from unregulated sources.

Flags

  • Not approved for human use by the FDA; sourced as a 'research chemical'.
  • Long-term safety profile for healthspan purposes is unknown.
  • Requires subcutaneous injection, which carries risks of infection and improper administration.
  • Purity and dosage accuracy from unregulated suppliers can be highly variable.

Verdict

A promising but high-risk experimental peptide for mitochondrial restoration.

Created

2026-04-24T00:11:46.733508Z

Model

Gemini 3.1 Pro (High)

Delivery

Route:
subcutaneous_injection
Scope:
  • systemic

Indication

Focus:
healthspan
Description:
SS-31 is a small peptide that selectively targets the inner mitochondrial membrane, binding to cardiolipin to stabilize mitochondrial structure and function. This enhances ATP production and reduces o...

Typical Protocol

  • Daily subcutaneous injections of 4-10 mg are explored in research contexts.