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Poly-L-lactic Acid (Sculptra)

Sculptra

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Meta Information

ID:sculptra
Name:Poly-L-lactic Acid (Sculptra)
Schema Version:1.5

Alternate Names

  • Sculptra

Intervention Type

procedure

Expected Cost Mean

Low Cost:
2000
High Cost:
5000
Cost Type:
procedure
Description:
Cost per treatment series; not covered by insurance.

Summary

Poly-L-lactic acid is a biocompatible, biodegradable synthetic polymer injected into the deep dermis to stimulate the body's own collagen production. Its healthspan relevance is primarily cosmetic, addressing age-related volume loss and skin laxity, which can positively impact psychosocial well-being but does not directly modulate systemic aging pathways.

Purpose

Stimulates collagen production to restore facial volume and skin structure.

Card Summary

A cosmetic injectable that stimulates the body's own collagen production to address age-related facial volume loss.

Drug Class

Drugs In Class

Empty Array

Impact

Score:
2
Justification:
Cosmetic effect on skin appearance with no direct systemic healthspan benefit.

Evidence

Grade:
A
Score:
9
Justification:
Multiple human RCTs confirm efficacy for cosmetic volume restoration and collagen synthesis.

Safety

Score:
4.5
Justification:
Requires skilled practitioner; risks include nodules, inflammation, and injection site reactions.

Flags

  • Risk of nodules or granulomas, particularly with improper injection technique or dilution.
  • Not recommended for individuals with autoimmune diseases or active skin inflammation.
  • Results are gradual, appearing over several months, and are not permanent.
  • Efficacy and safety are highly dependent on practitioner skill and experience.

Verdict

Effective for cosmetic skin aging, but offers no direct systemic healthspan benefit.

Created

2026-04-26T18:47:09.762105Z

Model

Gemini 3.1 Pro (High)

Delivery

Route:
none
Scope:
  • local

Indication

Focus:
healthspan
Description:
Poly-L-lactic acid is a biocompatible, biodegradable synthetic polymer injected into the deep dermis to stimulate the body's own collagen production. Its healthspan relevance is primarily cosmetic, ad...

Typical Protocol

  • An initial series of 2-3 treatments is typically performed 4-6 weeks apart.
  • Maintenance treatments are commonly administered every 1-2 years to sustain results.