Meta Information

ID:rhodiola-rosea

Name:Rhodiola Rosea

Schema Version:1.5

Alternate Names

• Golden Root
• Arctic Root
• Roseroot

Intervention Type

therapeutic_agent

Expected Cost Mean

Low Cost:

10

High Cost:

30

Cost Type:

monthly

Description:

Monthly cost for a standardized extract supplement, not covered by insurance.

Summary

Rhodiola rosea is an adaptogenic herb containing active compounds like rosavins and salidroside. It is thought to modulate the hypothalamic-pituitary-adrenal (HPA) axis and neurotransmitter systems, enhancing the body's resistance to physical and mental stress. From a healthspan perspective, its primary value lies in mitigating the chronic stress response, a known accelerator of aging processes, and improving cellular resilience.

Purpose

Adaptogen for stress resilience, fatigue reduction, and cognitive support.

Card Summary

An adaptogenic herb used to enhance resilience against physical and mental stressors, potentially mitigating stress-induced aging pathways and improving cognitive function.

Drug Class

Drugs In Class

Empty Array

Impact

Score:

4.5

Justification:

Targets stress-response pathways, but lacks direct evidence for systemic healthspan extension in humans.

Evidence

Grade:

B

Score:

6.5

Justification:

Multiple human RCTs show benefits for fatigue and stress, but study quality varies.

Safety

Score:

2.5

Justification:

Generally recognized as safe (GRAS) with a long history of use; mild side effects.

Flags

• Product quality varies; seek extracts standardized for rosavins and salidroside.
• May have a mild stimulating effect; avoid taking late in the day.
• Potential interactions with blood pressure, blood sugar, and antidepressant (MAOI, SSRI) medications.
• Consider cycling (e.g., 5 days on, 2 days off) to maintain efficacy.

Verdict

A useful, safe adaptogen for managing stress and fatigue.

Created

2026-04-26T18:04:32.790388Z

Model

Gemini 3.1 Pro (High)

Delivery

Route:

oral

Scope:

• systemic

Indication

Focus:

healthspan

Description:

Rhodiola rosea is an adaptogenic herb containing active compounds like rosavins and salidroside. It is thought to modulate the hypothalamic-pituitary-adrenal (HPA) axis and neurotransmitter systems, e...

Typical Protocol

• Take 200-600 mg daily of an extract standardized to 3% rosavins and 1% salidroside, often cycled.