Meta Information

ID:quercetin

Name:Quercetin

Schema Version:1.5

Title

Quercetin

Alternate Names

• Quercetin Dihydrate
• Sophoretin

Intervention Type

therapeutic_agent

Expected Cost Mean

Low Cost:

15

High Cost:

40

Cost Type:

monthly

Description:

Cost for a 30-day supply of standard or enhanced bioavailability formulations.

Summary

Quercetin is a plant flavonoid with antioxidant and anti-inflammatory properties. It is primarily investigated in a healthspan context for its potential as a senolytic, an agent that selectively induces apoptosis in senescent cells. By reducing the burden of these pro-inflammatory, non-dividing cells, quercetin may mitigate a key driver of age-related tissue dysfunction.

Purpose

A plant flavonoid that acts as a senolytic and anti-inflammatory.

Card Summary

A plant-derived flavonoid studied for its senolytic and anti-inflammatory effects, potentially reducing age-related cellular burden.

Drug Class

Drugs In Class

Empty Array

Impact

Score:

4.5

Justification:

Targeted benefit for cellular senescence, but human data on longevity outcomes is limited.

Evidence

Grade:

B

Score:

5.5

Justification:

Human trials exist for inflammation and specific conditions; senolytic effects are emerging.

Safety

Score:

3

Justification:

Generally recognized as safe (GRAS) with a good safety profile at typical doses.

Flags

• Poor bioavailability; often formulated with bromelain, vitamin C, or lipids (phytosome) to improve absorption.
• May interact with blood thinners (e.g., warfarin) and certain antibiotics (quinolones).
• High doses may pose a risk for individuals with pre-existing kidney disease.

Verdict

A promising experimental senolytic, but await more robust human data.

Created

2026-04-24T00:06:37.719237Z

Model

Gemini 3.1 Pro (High)

Delivery

Route:

oral

Scope:

• systemic

Indication

Focus:

healthspan

Description:

Quercetin is a plant flavonoid with antioxidant and anti-inflammatory properties. It is primarily investigated in a healthspan context for its potential as a senolytic, an agent that selectively induc...

Typical Protocol

• Take 500-1000 mg daily, often combined with bromelain or a phytosome for enhanced absorption.