Quercetin is a flavonoid with potent antioxidant, anti-inflammatory, and potential senolytic properties, meaning it may help clear senescent 'zombie' cells. The liposomal formulation encapsulates quercetin in a lipid sphere, dramatically increasing its poor natural bioavailability, allowing for more effective delivery to cells throughout the body.
Verdict
A promising, bioavailable supplement for inflammation, but direct human senolytic evidence is pending.
HEALTHSPAN IMPACT
Moderate
RISK LEVEL
Low
EVIDENCE GRADE
B
MONTHLY COST
$25 - $50
Protocol
- Typical daily doses range from 250 mg to 500 mg, taken with a meal to enhance absorption.
- Due to higher bioavailability, liposomal doses are often lower than standard quercetin protocols (which can exceed 1000 mg).
Flags
- May interact with antibiotics (quinolones), blood thinners (e.g., warfarin), and cyclosporine.
- Very high doses may potentially lead to kidney damage, though this is rare.
- Liposomal formulations significantly alter pharmacokinetics compared to standard quercetin.
- Quality and dosage can vary significantly between unregulated supplement brands.