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Noopept

N-phenylacetyl-L-prolylglycine ethyl ester, GVS-111

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Meta Information

ID:noopept
Name:Noopept
Schema Version:1.5

Alternate Names

  • N-phenylacetyl-L-prolylglycine ethyl ester
  • GVS-111

Intervention Type

therapeutic_agent

Expected Cost Mean

Low Cost:
10
High Cost:
30
Cost Type:
monthly
Description:
Cost for a typical monthly supply of bulk powder or capsules.

Summary

Noopept is a synthetic nootropic molecule purported to enhance cognitive function by modulating neurotransmitter systems and increasing neurotrophic factors like BDNF. Its relevance to healthspan is speculative, based on the hypothesis that preserving neuronal health and cognitive function is beneficial for longevity. However, there is no direct evidence that Noopept extends lifespan or significantly impacts the primary hallmarks of aging.

Purpose

A synthetic nootropic intended to support cognitive function and neuroprotection.

Card Summary

A synthetic nootropic with potential cognitive benefits but lacking direct healthspan evidence.

Drug Class

nootropics

Drugs In Class

Empty Array

Impact

Score:
2.5
Justification:
Lacks direct evidence for extending healthspan; cognitive benefits are not robustly proven.

Evidence

Grade:
C
Score:
3
Justification:
Primarily based on Russian clinical data and animal studies; lacks large-scale human RCTs.

Safety

Score:
7.2
Justification:
Unregulated research chemical with no long-term human safety data available.

Flags

  • Long-term safety in humans is unknown.
  • Not approved by the FDA for any medical use in the United States.
  • Potential side effects include irritability, headache, brain fog, and sleep disturbances.
  • Quality and purity of commercially available supplements can vary significantly.

Verdict

A speculative nootropic with unproven benefits and unknown long-term risks.

Created

2026-04-27T00:55:37.521460Z

Model

Gemini 3.1 Pro (High)

Delivery

Route:
oral
Scope:
  • systemic

Indication

Focus:
healthspan
Description:
Noopept is a synthetic nootropic molecule purported to enhance cognitive function by modulating neurotransmitter systems and increasing neurotrophic factors like BDNF. Its relevance to healthspan is s...

Typical Protocol

  • A typical dose is 10-30 mg daily, often divided into two or three doses.
  • Cycling protocols (e.g., 56 days on, 4 days off) are sometimes used to mitigate tolerance.