Mastic gum is a resin from the Pistacia lentiscus tree, traditionally used for gastrointestinal health. Its healthspan relevance is primarily linked to its potent antimicrobial and anti-inflammatory effects within the gut, particularly its demonstrated ability to combat Helicobacter pylori, a bacterium linked to gastritis, ulcers, and an increased risk of gastric cancer. By improving gut barrier function and reducing local inflammation, it may contribute to lower systemic inflammation, a key driver of aging.
Verdict
A safe, targeted intervention for improving gut health and combating H. pylori.
HEALTHSPAN IMPACT
Moderate
RISK LEVEL
Low
EVIDENCE GRADE
B
MONTHLY COST
$20 - $40
Protocol
- Typical protocols involve 1,000 mg daily, often divided into two doses before meals.
Flags
- May cause allergic reactions in individuals with allergies to the Pistacia family (e.g., pistachios).
- Not a substitute for standard medical therapy for severe H. pylori infections.
- High doses may cause mild digestive upset in some individuals.
- Theoretically may interact with antacids or blood thinners; consult a physician.