← Back to Directory

Mastic Gum

Chios Mastic, Pistacia lentiscus

Visual ViewRaw DataInteraction Data

Meta Information

ID:mastic-gum
Name:Mastic Gum
Schema Version:1.5

Alternate Names

  • Chios Mastic
  • Pistacia lentiscus

Intervention Type

therapeutic_agent

Expected Cost Mean

Low Cost:
20
High Cost:
40
Cost Type:
monthly
Description:
Monthly cost for standard 1,000 mg daily dose of encapsulated mastic gum.

Summary

Mastic gum is a resin from the Pistacia lentiscus tree, traditionally used for gastrointestinal health. Its healthspan relevance is primarily linked to its potent antimicrobial and anti-inflammatory effects within the gut, particularly its demonstrated ability to combat Helicobacter pylori, a bacterium linked to gastritis, ulcers, and an increased risk of gastric cancer. By improving gut barrier function and reducing local inflammation, it may contribute to lower systemic inflammation, a key driver of aging.

Purpose

A natural resin supporting gut health and reducing gastrointestinal inflammation.

Card Summary

A tree resin with antimicrobial and anti-inflammatory properties, primarily targeting gastrointestinal health and H. pylori.

Drug Class

Drugs In Class

Empty Array

Impact

Score:
4.2
Justification:
Primarily targets gastrointestinal health, a key but specific aspect of overall healthspan.

Evidence

Grade:
B
Score:
6.5
Justification:
Human RCTs exist for specific GI conditions, but not for longevity endpoints.

Safety

Score:
2.5
Justification:
Generally Recognized As Safe (GRAS) with a long history of human consumption.

Flags

  • May cause allergic reactions in individuals with allergies to the Pistacia family (e.g., pistachios).
  • Not a substitute for standard medical therapy for severe H. pylori infections.
  • High doses may cause mild digestive upset in some individuals.
  • Theoretically may interact with antacids or blood thinners; consult a physician.

Verdict

A safe, targeted intervention for improving gut health and combating H. pylori.

Created

2026-04-26T18:11:21.630627Z

Model

Gemini 3.1 Pro (High)

Delivery

Route:
oral
Scope:
  • systemic

Indication

Focus:
healthspan
Description:
Mastic gum is a resin from the Pistacia lentiscus tree, traditionally used for gastrointestinal health. Its healthspan relevance is primarily linked to its potent antimicrobial and anti-inflammatory e...

Typical Protocol

  • Typical protocols involve 1,000 mg daily, often divided into two doses before meals.