Meta Information
ID:magnesium-malate
Name:Magnesium Malate
Schema Version:1.5
Alternate Names
Empty Array
Intervention Type
therapeutic_agent
Expected Cost Mean
Low Cost:
10
High Cost:
25
Cost Type:
monthly
Description:
Widely available and inexpensive as a common dietary supplement.
Summary
Magnesium is an essential mineral and cofactor in over 300 enzymatic systems vital for healthspan, including ATP synthesis, DNA repair, and inflammation control. The malate form chelates magnesium with malic acid, a key intermediate in the cellular energy (Krebs) cycle, which may enhance absorption and support mitochondrial function, potentially reducing fatigue and muscle soreness.
Purpose
Supports cellular energy, muscle function, and nervous system health.
Card Summary
A form of magnesium chelated with malic acid, supporting cellular energy production (ATP) and potentially reducing muscle soreness and fatigue.
Drug Class
magnesium
Drugs In Class
Empty Array
Impact
Score:
5.5
Justification:
Essential mineral for core cellular processes; malate form targets energy production.
Evidence
Grade:
B
Score:
6.5
Justification:
Strong evidence for magnesium's importance, less for malate's specific advantages over other forms.
Safety
Score:
2.5
Justification:
Generally recognized as safe (GRAS); high doses may cause gastrointestinal distress.
Flags
- High doses can cause diarrhea or gastrointestinal upset.
- Individuals with kidney disease should consult a physician before supplementing.
- May interfere with the absorption of certain antibiotics (tetracyclines, quinolones) and bisphosphonates.
Verdict
A safe, affordable option for magnesium repletion, especially for energy.
Created
2026-04-25T22:23:42.998267Z
Model
Gemini 3.1 Pro (High)
Delivery
Route:
oral
Scope:
- systemic
Indication
Focus:
healthspan
Description:
Magnesium is an essential mineral and cofactor in over 300 enzymatic systems vital for healthspan, including ATP synthesis, DNA repair, and inflammation control. The malate form chelates magnesium wit...
Typical Protocol
- Take 200-400mg of elemental magnesium daily, often in the morning or early afternoon.