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Lutein

Zeaxanthin

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A carotenoid antioxidant protecting vision and potentially cognitive function.

Lutein is a carotenoid antioxidant that concentrates in the macula of the eye, filtering harmful blue light and neutralizing oxidative stress. Its primary healthspan relevance is in preserving vision by reducing the risk and progression of age-related macular degeneration (AMD) and cataracts. Emerging evidence also suggests a role in supporting cognitive function with age.

Verdict

A well-evidenced, safe supplement for preserving long-term vision.

HEALTHSPAN IMPACT

Moderate

RISK LEVEL

Very Low

EVIDENCE GRADE

A

MONTHLY COST

$5 - $25

Protocol

  • Daily supplementation of 10-20 mg of lutein, often combined with 2-4 mg of zeaxanthin.

Flags

  • Often formulated with zeaxanthin, as they work synergistically in the macula.
  • Absorption is significantly enhanced when taken with a meal containing dietary fat.
  • Smokers should consult a physician before taking high-dose carotenoid supplements.