Ivermectin is an anti-parasitic drug that functions by disrupting the nervous system of invertebrates. Its relevance to longevity is highly speculative, stemming from theories about potential anti-inflammatory, anti-viral, or senolytic properties. These proposed mechanisms lack substantiation from high-quality human evidence for healthspan extension.
Verdict
No credible evidence supports use for healthspan; potential risks outweigh benefits.
HEALTHSPAN IMPACT
Experimental
RISK LEVEL
High
EVIDENCE GRADE
D
MONTHLY COST
$20 - $100
Protocol
- No established healthspan protocol exists; use is primarily for parasitic infections.
Flags
- Requires a prescription and medical supervision for systemic use.
- Significant controversy and misinformation surround its use for non-approved indications.
- Interacts with warfarin and other medications metabolized by the CYP3A4 enzyme.
- Overdosing can lead to severe neurological side effects, including confusion, seizures, and coma.