Meta Information

ID:ivermectin

Name:Ivermectin

Schema Version:1.5

Alternate Names

• Stromectol
• Soolantra

Intervention Type

therapeutic_agent

Expected Cost Mean

Low Cost:

20

High Cost:

100

Cost Type:

procedure

Description:

Cost for a typical, short-term anti-parasitic prescription course.

Summary

Ivermectin is an anti-parasitic drug that functions by disrupting the nervous system of invertebrates. Its relevance to longevity is highly speculative, stemming from theories about potential anti-inflammatory, anti-viral, or senolytic properties. These proposed mechanisms lack substantiation from high-quality human evidence for healthspan extension.

Purpose

Anti-parasitic drug with speculative, unproven anti-inflammatory and senolytic effects.

Card Summary

An anti-parasitic drug with highly speculative and unproven benefits for human longevity.

Drug Class

avermectins

Drugs In Class

Empty Array

Impact

Score:

2.1

Justification:

No human data supports its use for longevity or healthspan extension.

Evidence

Grade:

D

Score:

1.5

Justification:

Longevity claims are based on theory and in-vitro data, lacking human trials.

Safety

Score:

6.5

Justification:

Prescription drug with significant side effects; high risk with unsupervised, off-label use.

Flags

• Requires a prescription and medical supervision for systemic use.
• Significant controversy and misinformation surround its use for non-approved indications.
• Interacts with warfarin and other medications metabolized by the CYP3A4 enzyme.
• Overdosing can lead to severe neurological side effects, including confusion, seizures, and coma.

Verdict

No credible evidence supports use for healthspan; potential risks outweigh benefits.

Created

2026-04-25T02:14:57.522352Z

Model

Gemini 3.1 Pro (High)

Delivery

Route:

oral

Scope:

• systemic

Indication

Focus:

healthspan

Description:

Ivermectin is an anti-parasitic drug that functions by disrupting the nervous system of invertebrates. Its relevance to longevity is highly speculative, stemming from theories about potential anti-inf...

Typical Protocol

• No established healthspan protocol exists; use is primarily for parasitic infections.