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Iron Sulfate

Ferrous Sulfate

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Corrects iron deficiency, standard first-line treatment.

Ferrous sulfate is the most common and inexpensive iron supplement used to treat iron deficiency and anemia. While highly effective at raising iron levels, it is notorious for causing gastrointestinal side effects such as constipation, nausea, and stomach upset.

Verdict

Essential for correcting deficiency; harmful if taken without medical need.

HEALTHSPAN IMPACT

Moderate

RISK LEVEL

Low

EVIDENCE GRADE

A

MONTHLY COST

$3 - $10

Protocol

  • Take 65 mg of elemental iron (325 mg ferrous sulfate) daily or every other day to correct diagnosed iron deficiency.
  • Dosage should be guided by regular ferritin, transferrin saturation, and CBC blood tests.

Flags

  • Only use if diagnosed with iron deficiency or insufficiency via blood tests.
  • Excess iron is a pro-oxidant and can accelerate aging and organ damage.
  • May interfere with absorption of zinc, manganese, and certain medications like levothyroxine.
  • Known to cause significant GI distress (constipation, nausea) in many users compared to chelated forms.