Iron is a critical component of hemoglobin for oxygen transport and a key cofactor in mitochondrial energy production. Iron bisglycinate is a highly bioavailable and gentle form used to correct iron deficiency, which, if unaddressed, impairs mitochondrial function, cellular repair, and cognitive health, thereby accelerating aging processes. It is a corrective intervention, not a general longevity supplement for those with sufficient iron levels.
Verdict
Essential for correcting deficiency; harmful if taken without medical need.
HEALTHSPAN IMPACT
Moderate
RISK LEVEL
Moderate
EVIDENCE GRADE
A
MONTHLY COST
$5 - $15
Protocol
- Take 25-50 mg daily or every other day to correct diagnosed iron deficiency.
- Dosage should be guided by regular ferritin, transferrin saturation, and CBC blood tests.
Flags
- Only use if diagnosed with iron deficiency or insufficiency via blood tests (e.g., ferritin).
- Excess iron is a pro-oxidant and can accelerate aging and organ damage.
- May interfere with absorption of zinc, manganese, and certain medications like levothyroxine.
- Iron bisglycinate is generally better tolerated with fewer gastrointestinal side effects than other forms.