Green tea extract's primary bioactive compound, epigallocatechin gallate (EGCG), is a potent antioxidant polyphenol. It is thought to support healthspan by activating pathways like AMPK, reducing oxidative stress, and potentially promoting cellular autophagy, which helps clear damaged cellular components.
Verdict
A useful antioxidant, but mind the dose to avoid liver risk.
HEALTHSPAN IMPACT
Moderate
RISK LEVEL
Low
EVIDENCE GRADE
B
MONTHLY COST
$10 - $30
Protocol
- Daily doses often range from 250-750 mg, standardized for high EGCG content.
Flags
- High doses (>800 mg EGCG/day) are associated with risk of liver injury.
- May reduce the absorption of iron and folic acid.
- Can interact with certain medications, including blood thinners and some heart medications.
- Best taken with food to minimize potential for stomach upset.