Chromium is an essential trace mineral involved in carbohydrate and lipid metabolism. It is theorized to enhance the action of insulin via a molecule called chromodulin, potentially improving cellular glucose uptake. While supplementation is popular for blood sugar control, its efficacy in healthy, non-deficient individuals for promoting healthspan is not well-established.
Verdict
Likely unnecessary for most, with minimal evidence for improving healthspan.
HEALTHSPAN IMPACT
Experimental
RISK LEVEL
Low
EVIDENCE GRADE
B
MONTHLY COST
$2 - $10
Protocol
- Typical daily doses range from 200 to 1000 micrograms (mcg), often as chromium picolinate.
Flags
- May interfere with medications for diabetes (e.g., insulin, metformin); consult a physician.
- Rare case reports link excessive intake to kidney damage.
- May interact with levothyroxine, NSAIDs, and antacids, affecting absorption.