Meta Information
ID:chromium
Name:Chromium
Schema Version:1.5
Alternate Names
- Chromium Picolinate
- Chromium Polynicotinate
- Chromium Chloride
Active Compound
chromium
Intervention Type
therapeutic_agent
Delivery
Route:
oral
Scope:
- systemic
Regulatory Status
- us:dietary_supplement
- eu:food_supplement
Indication
Focus:
healthspan
Description:
Aims to improve insulin sensitivity and glucose metabolism, which are key factors in metabolic health and aging.
Typical Protocol
- Typical daily doses range from 200 to 1000 micrograms (mcg), often as chromium picolinate.
Expected Cost Mean
Low Cost:
2
High Cost:
10
Cost Type:
monthly
Description:
Widely available and inexpensive over-the-counter dietary supplement, not covered by insurance.
Summary
Chromium is an essential trace mineral involved in carbohydrate and lipid metabolism. It is theorized to enhance the action of insulin via a molecule called chromodulin, potentially improving cellular glucose uptake. While supplementation is popular for blood sugar control, its efficacy in healthy, non-deficient individuals for promoting healthspan is not well-established.
Purpose
Essential trace mineral intended to support healthy insulin function and glucose metabolism.
Card Summary
A trace mineral supplement aimed at improving insulin sensitivity and blood sugar control.
Drug Class
null
Drugs In Class
- chromium-picolinate
- chromium-polynicotinate
Impact
Score:
2.5
Justification:
Minimal proven benefit for glycemic control in healthy, non-deficient individuals.
Evidence
Grade:
B
Score:
4.5
Justification:
Numerous human trials exist but show inconsistent and often negligible effects on glucose/insulin.
Safety
Score:
3
Justification:
Generally safe at recommended doses; rare reports of kidney issues with very high intake.
Flags
- May interfere with medications for diabetes (e.g., insulin, metformin); consult a physician.
- Rare case reports link excessive intake to kidney damage.
- May interact with levothyroxine, NSAIDs, and antacids, affecting absorption.
Verdict
Likely unnecessary for most, with minimal evidence for improving healthspan.
Created
2026-05-06T18:41:37.468120Z
Ai Model
Gemini 2.5 Pro (High)