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Chromium Polynicotinate

Chromium Niacinate, Chromium Nicotinate

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A mineral supplement intended to improve insulin sensitivity and glucose control.

Chromium is an essential trace mineral that may enhance the action of insulin, a hormone critical for metabolizing and storing carbohydrates, fat, and protein. By potentially improving insulin sensitivity, chromium polynicotinate is proposed to support stable blood glucose levels, which is a key factor in preventing age-related metabolic decline.

Verdict

Potentially useful for insulin resistance, but limited evidence for general healthspan.

HEALTHSPAN IMPACT

Experimental

RISK LEVEL

Low

EVIDENCE GRADE

B

MONTHLY COST

$10 - $25

Protocol

  • Typical doses range from 200 to 1000 micrograms (mcg) per day, often taken with meals to improve absorption.

Flags

  • High doses (>1000 mcg/day) have been linked to rare cases of kidney damage.
  • May interact with diabetes medications (e.g., insulin, metformin), requiring dose adjustments.
  • Individuals with pre-existing kidney or liver disease should consult a physician before use.