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3-Hydroxyanthranilic Acid

3-HAA

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Meta Information

ID:3-hydroxyanthranilic-acid
Name:3-Hydroxyanthranilic Acid
Schema Version:1.5

Alternate Names

  • 3-HAA

Intervention Type

therapeutic_agent

Expected Cost Mean

Low Cost:
0
High Cost:
0
Cost Type:
unquantifiable
Description:
Not available as a consumer supplement; sold only as a research chemical.

Summary

3-Hydroxyanthranilic Acid (3-HAA) is a metabolite of the amino acid tryptophan, produced via the kynurenine pathway. In animal models like C. elegans and mice, it has been shown to extend lifespan, likely by activating the NRF2 transcription factor which boosts endogenous antioxidant defenses. Its relevance and safety for human healthspan are entirely unknown and currently speculative.

Purpose

A tryptophan metabolite that may activate antioxidant pathways to extend lifespan.

Card Summary

An experimental tryptophan metabolite shown to extend lifespan in worms and mice by activating antioxidant defenses, but with no human data.

Drug Class

Drugs In Class

Empty Array

Impact

Score:
2.5
Justification:
Lifespan extension observed in worms and mice, but no human data exists.

Evidence

Grade:
C
Score:
3
Justification:
Evidence is limited to animal models (worms, mice) and in-vitro studies.

Safety

Score:
8.5
Justification:
No human safety data for supplementation; sold as a research chemical.

Flags

  • Not intended for human consumption and sold only as a research chemical.
  • Human safety profile for supplementation is completely unknown.
  • All evidence for lifespan extension comes from non-human animal models.
  • Part of the kynurenine pathway, which is complex and linked to inflammation.

Verdict

A purely experimental compound with no human data; not for use.

Created

2026-04-24T22:07:40.086046Z

Model

Gemini 3.1 Pro (High)

Delivery

Route:
oral
Scope:
  • systemic

Indication

Focus:
healthspan
Description:
3-Hydroxyanthranilic Acid (3-HAA) is a metabolite of the amino acid tryptophan, produced via the kynurenine pathway. In animal models like C. elegans and mice, it has been shown to extend lifespan, li...

Typical Protocol

  • No established human protocol exists; this is a research chemical not intended for consumption.