Zinc is an essential mineral critical for immune cell function, DNA repair, and as a cofactor for antioxidant enzymes like superoxide dismutase (SOD). Supplementation aims to counteract age-related declines in zinc levels and immune function (immunosenescence), thereby mitigating chronic inflammation and supporting cellular integrity.
Verdict
A key mineral for maintaining immune health, especially with age.
HEALTHSPAN IMPACT
Moderate
RISK LEVEL
Low
EVIDENCE GRADE
A
MONTHLY COST
$5 - $15
Protocol
- Typical daily supplementation ranges from 15-30 mg of elemental zinc.
- It is often recommended to take with food to minimize gastrointestinal upset.
- Long-term supplementation should be monitored or balanced with copper to prevent deficiency.
Flags
- Chronic high-dose intake (>40 mg/day) can induce copper deficiency and associated anemia.
- May interfere with the absorption of quinolone and tetracycline antibiotics.
- Can cause nausea or gastrointestinal upset, especially when taken on an empty stomach.