Meta Information

ID:zinc-carnosine

Name:Zinc Carnosine

Schema Version:1.5

Alternate Names

• Polaprezinc
• L-carnosine zinc complex
• PepZin GI

Active Compound

Zinc L-carnosine

Intervention Type

synergistic_therapy

Delivery

Route:

oral

Scope:

• local
• systemic

Regulatory Status

• us:dietary_supplement
• jp:rx_drug

Indication

Focus:

symptom_management

Description:

Primarily used for protecting and repairing the gastrointestinal mucosal lining, particularly for gastric ulcers, H. pylori infection, and indigestion.

Typical Protocol

• Standard doses are typically 75 mg of zinc carnosine (providing about 17 mg of elemental zinc) taken twice daily.

Expected Cost Mean

Low Cost:

15

High Cost:

30

Cost Type:

monthly

Description:

Widely available as an over-the-counter dietary supplement; not covered by insurance.

Summary

Zinc Carnosine is a chelated compound that dissociates slowly in the stomach, allowing it to adhere to the mucosal lining. This local action supports the integrity of the gut barrier, reduces inflammation, and promotes the healing of ulcerations. By maintaining gut health, it may indirectly support systemic health and reduce chronic low-grade inflammation originating from gut permeability, a key factor in healthspan.

Purpose

Supports gut lining integrity and reduces gastrointestinal inflammation.

Card Summary

A chelated compound that protects and repairs the stomach lining, primarily for ulcers and indigestion.

Drug Class

zinc

Drugs In Class

Empty Array

Impact

Score:

4.2

Justification:

Highly effective for a specific target (gut health), a key secondary healthspan pillar.

Evidence

Grade:

A

Score:

8.5

Justification:

Multiple human RCTs and approved prescription drug status in Japan for gastric ulcers.

Safety

Score:

2.5

Justification:

Generally recognized as safe at standard doses; potential for copper imbalance with long-term use.

Flags

• Long-term high-dose zinc intake can interfere with copper absorption, leading to deficiency.
• Best taken on an empty stomach for maximal gastric coating effect.

Verdict

Excellent for targeted gut lining support, not a primary longevity agent.

Created

2026-05-06T18:39:00.922502Z

Ai Model

Gemini 2.5 Pro (High)