Zinc is an essential mineral that functions as a cofactor for hundreds of enzymes involved in critical processes like immune function, DNA synthesis and repair, and antioxidant defense. Maintaining optimal zinc status is crucial for immune cell development and signaling, particularly T-cell function, which tends to decline with age. By supporting these fundamental cellular operations, zinc helps maintain systemic resilience against stressors and pathogens, a cornerstone of healthspan.
Verdict
Correct deficiency to support foundational immune and cellular health.
HEALTHSPAN IMPACT
Moderate
RISK LEVEL
Low
EVIDENCE GRADE
A
MONTHLY COST
$5 - $15
Protocol
- Take 15-30 mg of a chelated form like picolinate or gluconate daily with food.
- Ensure adequate copper intake (e.g., 1-2 mg) to prevent zinc-induced deficiency.
Flags
- Chronic high doses (>40 mg/day) can interfere with copper absorption, leading to deficiency.
- May cause nausea or stomach upset, especially when taken on an empty stomach.
- Can reduce the absorption of quinolone and tetracycline antibiotics.
- Zinc sufficiency is key; excessive intake provides no additional healthspan benefit.