Zeaxanthin is a carotenoid antioxidant that, along with lutein, accumulates in the macula of the eye. Its primary mechanism is filtering high-energy blue light and neutralizing oxidative stress, directly protecting retinal cells from damage. This is highly relevant for healthspan as it helps prevent or slow the progression of age-related macular degeneration (AMD), a leading cause of vision loss that severely impacts quality of life and independence in later years.
Verdict
A well-evidenced, safe supplement for protecting long-term vision health.
HEALTHSPAN IMPACT
Moderate
RISK LEVEL
Low
EVIDENCE GRADE
A
MONTHLY COST
$10 - $30
Protocol
- A typical dose is 2 mg daily, often combined with 10 mg of lutein for eye health.
Flags
- Almost always formulated and studied in combination with lutein.
- Smokers should be cautious with high-dose carotenoid supplements due to risks associated with beta-carotene.