Vitamin B5 is an essential nutrient that serves as the precursor to Coenzyme A (CoA), a critical molecule in cellular metabolism. CoA is vital for the citric acid cycle (energy production), as well as the synthesis and breakdown of fatty acids. Maintaining adequate B5 levels is foundational for cellular energy and metabolic health, though supplementation beyond dietary intake has not been shown to extend healthspan in non-deficient individuals.
Verdict
Essential nutrient easily obtained from diet; supplementation is generally unnecessary.
HEALTHSPAN IMPACT
Experimental
RISK LEVEL
Very Low
EVIDENCE GRADE
B
MONTHLY COST
$5 - $15
Protocol
- The Recommended Dietary Allowance (RDA) for adults is 5 mg per day, typically obtained through a balanced diet.
- Supplementation is generally not required for healthspan as deficiency is extremely rare.
Flags
- Very high doses (grams per day) may cause mild diarrhea or stomach upset.
- No significant drug interactions are widely reported.