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Vitamin B2

Riboflavin, Vitamin G

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Meta Information

ID:vitamin-b2
Name:Vitamin B2
Schema Version:1.5

Alternate Names

  • Riboflavin
  • Vitamin G

Active Compound

riboflavin

Intervention Type

therapeutic_agent

Delivery

Route:
oral
Scope:
  • systemic

Regulatory Status

  • us:dietary_supplement
  • us:otc_drug

Indication

Focus:
healthspan
Description:
Supports cellular energy production and redox reactions, essential for maintaining metabolic health and preventing deficiency-related decline.

Typical Protocol

  • The Recommended Dietary Allowance (RDA) is 1.1-1.3 mg daily, typically met through a balanced diet.
  • Supplementation is generally only necessary to correct a dietary deficiency or for specific medical indications.
  • High doses of up to 400 mg daily are used under medical supervision for migraine prophylaxis.

Expected Cost Mean

Low Cost:
5
High Cost:
15
Cost Type:
monthly
Description:
Widely available and inexpensive over-the-counter supplement; generally not covered by insurance.

Summary

Riboflavin is a crucial precursor to the coenzymes FAD and FMN, which are essential for cellular energy production via the electron transport chain and numerous metabolic redox reactions. Ensuring adequate riboflavin levels is foundational for maintaining mitochondrial function and overall metabolic health, preventing age-related decline associated with energy deficits.

Purpose

Essential coenzyme for cellular energy production and metabolism.

Card Summary

A fundamental B-vitamin essential for converting food into cellular energy, supporting mitochondrial health.

Drug Class

null

Drugs In Class

Empty Array

Impact

Score:
4.5
Justification:
Essential for preventing deficiency, but limited evidence for supra-physiological doses enhancing healthspan.

Evidence

Grade:
A
Score:
9
Justification:
Vast body of evidence establishes its essential role in human cellular metabolism.

Safety

Score:
2.5
Justification:
Water-soluble vitamin with excess readily excreted; high doses are well-tolerated.

Flags

  • High doses cause a harmless, bright yellow-orange discoloration of urine (flavinuria).
  • May interfere with certain lab tests, including urinalysis and catecholamine measurements.
  • May decrease the absorption of tetracycline antibiotics; separate doses by several hours.

Verdict

Essential nutrient best obtained from diet; supplement only if deficient.

Created

2026-05-06T18:22:57.001056Z

Ai Model

Gemini 2.5 Pro (High)