Meta Information
ID:valerian-root
Name:Valerian Root
Schema Version:1.5
Alternate Names
- Valeriana officinalis
- Garden Heliotrope
Intervention Type
therapeutic_agent
Expected Cost Mean
Low Cost:
10
High Cost:
25
Cost Type:
monthly
Description:
Widely available over-the-counter herbal supplement for sleep.
Summary
Valerian root is an herbal supplement thought to promote sleep and reduce anxiety by modulating the neurotransmitter GABA. Its primary relevance to healthspan is indirect; by potentially improving sleep quality, it supports foundational processes like cellular repair, glymphatic clearance, and hormonal regulation, which are critical for long-term brain and metabolic health.
Purpose
An herbal supplement used to improve sleep quality and reduce anxiety.
Card Summary
An herbal supplement that may improve sleep quality by increasing GABA, indirectly supporting cellular repair.
Drug Class
Drugs In Class
Empty Array
Impact
Score:
4.2
Justification:
Indirectly supports healthspan by improving sleep quality, a key recovery process.
Evidence
Grade:
B
Score:
5.5
Justification:
Multiple human trials and meta-analyses exist, but results are inconsistent and modest.
Safety
Score:
3
Justification:
Generally recognized as safe for short-term use with mild, infrequent side effects.
Flags
- May interact with sedatives, alcohol, and other CNS depressants.
- Long-term safety data beyond a few months is limited.
- Avoid during pregnancy and breastfeeding due to lack of safety data.
- May cause mild side effects like headache, dizziness, or stomach upset.
Verdict
A low-risk, low-cost option for mild sleep issues; evidence is mixed.
Created
2026-04-26T17:44:41.040864Z
Model
Gemini 3.1 Pro (High)
Delivery
Route:
oral
Scope:
- systemic
Indication
Focus:
healthspan
Description:
Valerian root is an herbal supplement thought to promote sleep and reduce anxiety by modulating the neurotransmitter GABA. Its primary relevance to healthspan is indirect; by potentially improving sle...
Typical Protocol
- Take 300-600 mg of standardized extract containing 0.8% valerenic acid 30-120 minutes before bedtime.