Meta Information
ID:topical-coq10
Name:CoQ10
Schema Version:1.5
Alternate Names
- Ubiquinone (Topical)
- Ubidecarenone (Topical)
Intervention Type
therapeutic_agent
Expected Cost Mean
Low Cost:
15
High Cost:
75
Cost Type:
monthly
Description:
Cost for a 30-day supply of a quality CoQ10 serum or cream.
Covered By Insurance:
False
Summary
Coenzyme Q10 is a vital antioxidant naturally present in skin cells, but its levels decline with age. Topical application may help neutralize free radicals generated by UV radiation and pollution, potentially reducing the appearance of fine lines and supporting cellular energy production within the skin.
Purpose
Topical antioxidant to mitigate skin photoaging and oxidative stress.
Card Summary
A topical antioxidant that may reduce visible signs of skin aging by combating UV-induced oxidative stress.
Drug Class
Drugs In Class
Empty Array
Impact
Score:
2.5
Justification:
Limited to cosmetic skin benefits; no evidence for systemic healthspan or longevity impact.
Evidence
Grade:
B
Score:
5.5
Justification:
Some small human trials show cosmetic skin benefits, but lacks large-scale RCTs.
Safety
Score:
1.5
Justification:
Generally recognized as safe for topical use with very low risk of irritation.
Flags
- Efficacy is highly dependent on formulation, concentration, and skin penetration.
- Benefits are localized to the skin and do not affect systemic aging.
- May cause mild skin irritation or allergic reaction in sensitive individuals.
Verdict
A safe cosmetic for skin appearance, not a systemic longevity intervention.
Created
2026-04-26T18:26:21.792324Z
Model
Gemini 3.1 Pro (High)
Delivery
Route:
topical_skin
Scope:
- local
Is Skin Health
True
Indication
Focus:
healthspan
Description:
Coenzyme Q10 is a vital antioxidant naturally present in skin cells, but its levels decline with age. Topical application may help neutralize free radicals generated by UV radiation and pollution, pot...
Typical Protocol
- Apply a 0.3% to 1% concentration cream or serum to the face once or twice daily.