Meta Information

ID:telmisartan

Name:Telmisartan

Schema Version:1.5

Alternate Names

• Micardis

Intervention Type

therapeutic_agent

Expected Cost Mean

Low Cost:

10

High Cost:

25

Cost Type:

monthly

Description:

Generic prescription cost; often covered by insurance for approved indications.

Summary

Telmisartan is an Angiotensin II Receptor Blocker (ARB) that lowers blood pressure by blocking the vasoconstricting effects of angiotensin II. Uniquely among ARBs, it also acts as a partial PPAR-gamma agonist, which can improve insulin sensitivity and metabolic health, making it a dual-threat agent against cardiometabolic aging.

Purpose

An ARB that lowers blood pressure and improves metabolic health.

Card Summary

An Angiotensin II Receptor Blocker (ARB) that lowers blood pressure, reduces inflammation, and uniquely activates PPAR-gamma to improve metabolic function.

Drug Class

arbs

Drugs In Class

Empty Array

Impact

Score:

7.5

Justification:

Potently lowers blood pressure and offers unique metabolic benefits via PPAR-gamma agonism.

Evidence

Grade:

A

Score:

9

Justification:

Extensive human RCTs confirm potent blood pressure reduction and cardiovascular risk mitigation.

Safety

Score:

4.5

Justification:

Generally well-tolerated prescription drug; requires monitoring for blood pressure and potassium levels.

Flags

• Contraindicated during pregnancy due to risk of fetal injury.
• Risk of hyperkalemia (high potassium), especially with kidney issues or potassium supplements.
• May cause hypotension (low blood pressure), dizziness, or lightheadedness.
• Rare but serious risk of angioedema (swelling).
• Requires a prescription and medical supervision.

Verdict

A top-tier ARB for blood pressure control with unique metabolic benefits.

Created

2026-04-27T00:50:00.919459Z

Model

Gemini 3.1 Pro (High)

Delivery

Route:

oral

Scope:

• systemic

Indication

Focus:

healthspan

Description:

Telmisartan is an Angiotensin II Receptor Blocker (ARB) that lowers blood pressure by blocking the vasoconstricting effects of angiotensin II. Uniquely among ARBs, it also acts as a partial PPAR-gamma...

Typical Protocol

• Typical longevity-focused protocols involve daily doses of 20mg to 40mg, often taken at night.