Sustained-release Vitamin C (ascorbic acid) is formulated to dissolve slowly over several hours, maintaining more stable plasma concentrations than immediate-release forms. As a crucial antioxidant, it neutralizes free radicals, supports immune cell function, and is essential for collagen production, which is vital for skin, joint, and vascular health. This delivery method aims to improve absorption and reduce potential gastrointestinal upset from large, single doses.
Verdict
A safe, foundational antioxidant with theoretical benefits from its sustained-release formulation.
HEALTHSPAN IMPACT
Moderate
RISK LEVEL
Low
EVIDENCE GRADE
A
MONTHLY COST
$10 - $25
Protocol
- Take 500mg to 1000mg once or twice daily to maintain stable plasma levels throughout the day.
Flags
- Sustained-release formulations may reduce the risk of gastrointestinal upset compared to high-dose immediate-release forms.
- Very high doses (>2000mg/day) can increase the risk of kidney stones in susceptible individuals.
- May interfere with certain lab tests, including blood glucose monitoring.
- Individuals with hemochromatosis should use caution due to increased iron absorption.