Strontium

Strontium is a trace mineral chemically similar to calcium that incorporates into bone. It is thought to support bone health by simultaneously stimulating osteoblasts (bone-building cells) and inhibiting osteoclasts (bone-resorbing cells). Its primary relevance to healthspan is mitigating age-related bone loss (osteoporosis), which helps reduce fracture risk and maintain mobility and independence in later life.

Verdict

A targeted tool for bone density, but with notable safety considerations.

Protocol

• Daily doses of 340mg to 680mg of elemental strontium are often used for bone health, taken away from calcium intake.

Flags

• Must be taken several hours apart from calcium supplements or calcium-rich foods to avoid absorption competition.
• Can artificially inflate Bone Mineral Density (BMD) readings on DEXA scans, complicating interpretation.
• The prescription form, strontium ranelate (not available in the US), is associated with increased risk of blood clots (VTE) and serious cardiovascular events.
• Not recommended for individuals with a history of, or high risk for, cardiovascular disease or VTE.
• Long-term safety data for the common supplement form (strontium citrate) is limited.