Meta Information
ID:silicon
Name:Orthosilicic acid
Schema Version:1.5
Alternate Names
- OSA
- Choline-stabilized orthosilicic acid (ch-OSA)
- Silica
Intervention Type
therapeutic_agent
Expected Cost Mean
Low Cost:
20
High Cost:
40
Cost Type:
monthly
Description:
Cost for a one-month supply of choline-stabilized orthosilicic acid (ch-OSA) supplements.
Summary
Silicon is a trace mineral essential for the synthesis of collagen and glycosaminoglycans, critical components of all connective tissues. Its primary healthspan relevance lies in supporting skeletal integrity by improving bone mineral density and promoting the health and elasticity of skin, hair, and nails, which are visible markers of aging.
Purpose
Supports bone density, collagen production, and connective tissue health.
Drug Class
Drugs In Class
Empty Array
Impact
Score:
4.2
Justification:
Targeted benefits for bone density and connective tissue health, not a systemic aging modulator.
Evidence
Grade:
B
Score:
6.5
Justification:
Human RCTs show benefits for bone density and skin, but more large-scale trials are needed.
Safety
Score:
2.5
Justification:
Generally Recognized As Safe (GRAS) at typical supplemental doses with a good safety profile.
Flags
- Bioavailability varies greatly; choline-stabilized orthosilicic acid (ch-OSA) is a well-studied form.
- Individuals with kidney disorders should consult a physician before supplementing with high doses.
Verdict
A reasonable supplement for targeted bone and connective tissue support.
Created
2026-04-26T18:30:44.349975Z
Model
Gemini 3.1 Pro (High)
Delivery
Route:
oral
Scope:
- systemic
Indication
Focus:
healthspan
Description:
Silicon is a trace mineral essential for the synthesis of collagen and glycosaminoglycans, critical components of all connective tissues. Its primary healthspan relevance lies in supporting skeletal i...
Typical Protocol
- Take 5-10 mg of elemental silicon daily, often as choline-stabilized orthosilicic acid (ch-OSA).