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Schisandra

Schisandra chinensis, Five-Flavor Berry, Wu Wei Zi

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Meta Information

ID:schisandra
Name:Schisandra
Schema Version:1.5

Alternate Names

  • Schisandra chinensis
  • Five-Flavor Berry
  • Wu Wei Zi

Intervention Type

therapeutic_agent

Expected Cost Mean

Low Cost:
10
High Cost:
30
Cost Type:
monthly
Description:
Cost for a one-month supply of standardized extract capsules or powder.

Summary

Schisandra is an adaptogenic herb containing lignans that may enhance resilience to stress by modulating the HPA axis and providing antioxidant effects. Its relevance to healthspan lies in its potential to protect against cellular damage, support liver detoxification, and improve physical and cognitive performance under stress.

Purpose

Adaptogen for stress resilience, liver support, and antioxidant defense.

Card Summary

An adaptogenic berry used to enhance stress resilience and liver function.

Drug Class

Drugs In Class

Empty Array

Impact

Score:
3.8
Justification:
Primarily provides adaptogenic stress support with limited direct evidence for extending human healthspan.

Evidence

Grade:
B
Score:
4.5
Justification:
Some human trials for performance and stress, but lacks large-scale longevity studies.

Safety

Score:
3.2
Justification:
Generally well-tolerated but can interact with drugs metabolized by CYP3A4 enzymes.

Flags

  • May interact with drugs metabolized by CYP3A4 enzymes, such as warfarin or immunosuppressants.
  • Avoid use during pregnancy and breastfeeding due to insufficient safety data.
  • May cause mild gastrointestinal upset or decreased appetite in sensitive individuals.

Verdict

A plausible adaptogen for stress, but not a primary longevity intervention.

Created

2026-04-26T18:05:45.498873Z

Model

Gemini 3.1 Pro (High)

Delivery

Route:
oral
Scope:
  • systemic

Indication

Focus:
healthspan
Description:
Schisandra is an adaptogenic herb containing lignans that may enhance resilience to stress by modulating the HPA axis and providing antioxidant effects. Its relevance to healthspan lies in its potenti...

Typical Protocol

  • Take 500-2000mg of standardized extract daily, often divided into two doses.