Meta Information
ID:saffron-extract
Name:Saffron Extract
Schema Version:1.5
Alternate Names
- Crocus sativus
- Safranal
- Crocin
Intervention Type
therapeutic_agent
Expected Cost Mean
Low Cost:
15
High Cost:
40
Cost Type:
monthly
Description:
Cost for a one-month supply of standardized saffron extract capsules.
Summary
Saffron extract contains active compounds like crocin and safranal, which exert potent antioxidant and anti-inflammatory effects. Its primary mechanism involves modulating neurotransmitters, particularly serotonin, which underpins its use for mood support. From a healthspan perspective, its value lies in mitigating neuroinflammation and oxidative stress, key drivers of age-related cognitive decline.
Purpose
Antioxidant and neuroprotective agent for mood and cognitive function.
Card Summary
A plant extract with antioxidant properties studied for mood and cognitive support.
Drug Class
Drugs In Class
Empty Array
Impact
Score:
4.5
Justification:
Targeted benefits for mood and neuro-inflammation, not a systemic longevity driver.
Evidence
Grade:
A
Score:
8.5
Justification:
Multiple meta-analyses and human RCTs support its use for mood and cognition.
Safety
Score:
3.5
Justification:
Generally safe at typical doses, but high doses are toxic.
Flags
- High doses (>5 grams) are toxic and potentially lethal.
- May interact with blood pressure, anticoagulant, and antiplatelet medications.
- Use with caution if taking SSRIs or other serotonergic drugs due to potential additive effects.
- Avoid during pregnancy due to potential uterine-stimulant effects.
Verdict
A well-evidenced supplement for mood support with potential neuroprotective benefits.
Created
2026-04-27T00:48:16.208939Z
Model
Gemini 3.1 Pro (High)
Delivery
Route:
oral
Scope:
- systemic
Indication
Focus:
healthspan
Description:
Saffron extract contains active compounds like crocin and safranal, which exert potent antioxidant and anti-inflammatory effects. Its primary mechanism involves modulating neurotransmitters, particula...
Typical Protocol
- A standard daily dose is 30 mg, often divided into two 15 mg doses.