Meta Information
ID:resveratrol-liposomal
Name:Liposomal Resveratrol
Schema Version:1.5
Alternate Names
- Liposomal Trans-Resveratrol
Active Compound
resveratrol
Intervention Type
therapeutic_agent
Delivery
Route:
oral
Scope:
- systemic
Regulatory Status
- us:dietary_supplement
- eu:food_supplement
Indication
Focus:
healthspan
Description:
Targeting cellular aging pathways, such as sirtuin activation and mitochondrial function, for general healthspan improvement.
Typical Protocol
- Typical daily doses range from 150 mg to 500 mg, taken once daily.
- Often taken with a source of fat, like olive oil or yogurt, to further enhance absorption.
Expected Cost Mean
Low Cost:
25
High Cost:
60
Cost Type:
monthly
Description:
Cost for a one-month supply of a quality-tested liposomal formulation; not insurance covered.
Summary
Resveratrol is a polyphenol that activates sirtuins, particularly SIRT1, which are key regulators of cellular health and aging. The liposomal formulation encapsulates resveratrol in lipid spheres, significantly enhancing its poor natural bioavailability and allowing for more effective delivery to cells. This improved absorption aims to more reliably mimic the cellular benefits observed in preclinical studies, such as improved mitochondrial function and reduced inflammation.
Purpose
A highly bioavailable polyphenol to activate sirtuin longevity pathways.
Card Summary
A highly bioavailable form of resveratrol designed to activate cellular longevity pathways like sirtuins, though human evidence for systemic healthspan benefits remains limited.
Drug Class
null
Drugs In Class
Empty Array
Impact
Score:
3.5
Justification:
Primarily preclinical evidence; human trials show limited, inconsistent benefits on major healthspan markers.
Evidence
Grade:
B
Score:
4
Justification:
Mixed results in human trials, with strong preclinical data not yet translating robustly.
Safety
Score:
3.2
Justification:
Generally well-tolerated but can cause GI issues and interact with anticoagulant medications.
Flags
- May interact with blood thinners like warfarin, increasing bleeding risk.
- Can inhibit cytochrome P450 enzymes, potentially altering the metabolism of various medications.
- High doses may cause gastrointestinal side effects such as nausea or diarrhea.
- The long-term effects of sustained sirtuin activation in humans are not fully understood.
Verdict
A bioavailability-enhanced supplement with promising theory but currently lacking strong human evidence.
Created
2026-06-12T17:48:06.242952Z
Ai Model
Gemini 2.5 Pro (High)