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Pyrroloquinoline Quinone (PQQ)

PQQ

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Meta Information

ID:pqq
Name:Pyrroloquinoline Quinone (PQQ)
Schema Version:1.5

Alternate Names

  • PQQ

Active Compound

Pyrroloquinoline quinone

Intervention Type

therapeutic_agent

Delivery

Route:
oral
Scope:
  • systemic

Regulatory Status

  • us:dietary_supplement

Indication

Focus:
healthspan
Description:
Supports mitochondrial function and acts as a potent antioxidant, promoting cellular energy and resilience.

Typical Protocol

  • Common dosages range from 10 mg to 20 mg daily, typically taken with food for optimal absorption.

Expected Cost Mean

Low Cost:
15
High Cost:
40
Cost Type:
monthly
Description:
Monthly cost for PQQ supplementation, generally not covered by insurance.

Summary

PQQ is a redox cofactor that plays a critical role in mitochondrial biogenesis, the growth of new mitochondria, and acts as a powerful antioxidant. It helps protect cells from oxidative damage, supports energy metabolism, and potentially improves cognitive function, contributing to cellular resilience and overall healthspan.

Purpose

Enhances mitochondrial function and antioxidant defense for cellular health.

Card Summary

PQQ enhances mitochondrial biogenesis and acts as a potent antioxidant, protecting cells from damage and supporting energy metabolism, contributing to overall cellular health and potentially cognitive function.

Drug Class

null

Drugs In Class

Empty Array

Impact

Score:
4.5
Justification:
Effective for mitochondrial support and antioxidant defense, specific pathways.

Evidence

Grade:
B
Score:
5.5
Justification:
Limited human trials show some benefits, more robust studies needed.

Safety

Score:
3
Justification:
Generally well-tolerated, few reported side effects at typical doses.

Flags

  • Potential for mild gastrointestinal upset at higher doses.

Verdict

May support mitochondrial health and antioxidant capacity; moderate evidence.